Israeli and American scientists have jointly discovered a new link to Alzheimer's disease.

Scientists from Columbia University and the Hebrew University of Jerusalem conducted a large-scale study analyzing more than 1.6 million brain cells from older adults to identify cellular changes associated with Alzheimer's disease. The results, published in the journal Nature, open up new prospects for preventing this type of dementia.

One of the study's authors emphasized that Alzheimer's disease is a disorder of interactions between different cellular communities in the brain. New technologies have allowed scientists to study the brain at the cellular level, tracking changes at different stages of the disease, starting from the early ones.

Using machine learning techniques, scientists have discovered that microglial cells, which are responsible for the brain’s immune functions, are the first to trigger the development of Alzheimer’s disease. This discovery could help develop new approaches to treatment by returning brain cells to a healthy state.

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